05 October 2020

Haplo Group and you and disease!

Did you do your DNA yet.  You can learn your Haplogroup from it.

Here is a explanation of it from Wikipedia:


 Haplogroup

From Wikipedia, the free encyclopedia

...haplotype is a group of alleles in an organism that are inherited together from a single parent,[1][2] and a haplogroup (haploid from the Greekἁπλοῦςhaploûs, "onefold, simple" and English: Group) is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation.[3][4] More specifically, a haplogroup is a combination of alleles at different chromosomal regions that are closely linked and that tend to be inherited together. As a haplogroup consists of similar haplotypes, it is usually possible to predict a haplogroup from haplotypes. Haplogroups pertain to a single line of descent. As such, membership of a haplogroup, by any individual, relies on a relatively small proportion of the genetic material possessed by that individual.


.

Then did you know your Haplogroup can determine if you can get certain illnesses as explained here:  



From their : Human Molecular Genetics

::Population Genetics and Disease Susceptibility: Characterization of Central European Haplogroups By mtDNA Gene Mutations, Correlation with D Loop Variants and Association With Disease 
Sabine Hofmann, Michaela Jaksch, Reimar Bezold, Sabine Mertens, Simone Aholt, Armin Paprotta, Klaus-Dieter Gerbitz Author Notes::

Human Molecular Genetics, Volume 6, Issue 11, October 1997, Pages 1835–1846, https://doi.org/10.1093/hmg/6.11.1835
Published:
 
01 October 1997

Their Abstract as follows: 

Abstract

Mitochondrial (mt)DNA haplogroups in a German control group (n = 67) were characterized by screening mitochondrial coding regions encompassing most of the ND, tRNA and cyt b genes. We used a PCR-SSCP screening approach followed by direct sequencing of polymorphic mtDNA fragments. Five major mtDNA lineages, diverging in at least nine different haplogroups, could be defined by characteristic polymorphic sites in mitochondrial genes. Additional sequencing of two hypervariable segments (HVS-I and II) of the non-coding displacement (D) loop in all control subjects revealed that certain D loop variants were strongly correlated with lineages and haplogroups, while others represented hotspots occurring frequently in different haplogroups. The existence of identified lineages and haplogroups received support from data in the literature, obtained by use of different approaches. Subsequently, we investigated four disease groups for association with these haplogroups: (i) LHON patients (n = 55) carrying at least one of the primary/intermediate LHON mutations at nt 3460, 11778, 14484 and/or 15257; (ii) patients suffering from Wolfram or DIDMOAD syndrome(n = 8); (iii) MELAS patients (n = 9); (iv) a group of children, who died from ‘sudden infant death syndrome’ (SIDS) (n = 9). The distribution patterns among the haplogroups of the disease groups (LHON, DIDMOAD and SIDS) differed considerably from the control population. LHON and DIDMOAD were significantly under-represented in the most frequent German haplogroup DC, but were concentrated in a mtDNA lineage defined by polymorphisms at nt 4216+11251+16126. As this lineage diverged into two precisely defined haplogroups, LHON and DIDMOAD could be assigned to the two haplogroups separately. Strikingly, SIDS was often found in association with two rare German haplogroups. MELAS patients were equally distributed among German haplogroups and, moreover, did not reveal any accumulation of specific D loop variants. We conclude that certain European mtDNA haplogroups define a genetic susceptibility basis for various disorders.


As you see in the abstract their are very telling illnesses/disease that have all to do with your Haplogroup.  Amazing and sad as stated in the abstract with SIDS.

So can your Haplogroup also keep you from becoming ill from Pandemics?  I tried to find this out.  There are no current studies on it.  Who knows in a few short years someone may take an interest an we might learn a result.

So you did do your DNA!  Did you know there is a service that can provide you with many answers.  I uploaded my raw DNA in a service called Prometheas.  It can tell you what color eyes you should have.  I had to share with them that nope my eyes are not so yellow as they say.  

It can let you know if Parkensons disease in in there too.  But mine was negative.  Lucky me and my decendants.


Covid Pandemic and ETC...

 So your Ancestor created you before sub-coming to a Pandemic. 

That's great because here you are.  There are still babies being created and born here in Covid-19 times.   How many of them will remember the pandemic Covid-19 and pass the lessons learned to the New Generations?


   We can be sure most likely we will not be around.  Write in your journals.  Keep your story going.


09 May 2019

Geneaolgy and Chess Game

Chess

Recently I read the book"Queen of Katwe"  true story of a very young chess champion.  Got me thinking.

How many of you have played or still play chess.  In family history are we not kinda doing the same.  The King is the elusive Ancestor.  We are moving around, could be physically or sitting on your bottom using the internet.  Seeking out that ancestor who we believe is the right one.

Ah how happy we are not to have taken a DRAW,  that when we actually win this very long tedious game of ancestor chess we are successful in adding the correct name into our tree.

I learned chess when I was a teen babysitting for one of my regular babysitting jobs.  The mom was German.  She had been teaching the children.  The daughter Brenda, set me on the road to chess.  I could not get my siblings interested.  There were no chess clubs at school.  I learned as much as I could I tried to improve my game by reading the extremely boring old people chess book. 

I would teach what I knew mostly to children, it was great when they could suppass me.

Then when I had my own children I taught them .  My older son excelled in it. 

I have not played in a long time on a board,  cause now I play the ancestoral game of catch the ancestor.

27 August 2018

Quebec Marriage Contract

Marriage contract, Quebec, family, Marriage, French traditions, French
My Ancestors in Quebec
365 Days a Year, 
365 Family History-Genealogy Rules 

18.
If you did your DNA, did you also find your Haplo group?
365 Days a Year, 
365 Family History-Genealogy Rules 

17.
32 sets of GreatGreatGreatGrandparents.  Do you know all of your 
Yet? Get busy if you don't.

25 August 2018

365 Days a Year, 
365 Family History-Genealogy Rules 

16.
It's in the mix.
Your DNA mix is who you are.  Eye, Hair, skin color.  Shape of eyes, teeth, nose. Sound of your voice.  It's all in your DNA Mix.

365 Days a Year, 
365 Family History-Genealogy Rules 

15.

With DNA comes your Haplo Group.

Your origins tru the oldest female lines.  
Girls and Women only carry their Mothers.  It is continuously passed on through the generations.  Mother to daughter, Mother to son.

A Man will never pass his Mothers Haplo group on to his children.

Curious how the children of Israel state that they are Jewish through their mother. 

24 August 2018

365 Days a Year, 
365 Family History-Genealogy Rules 

14.   Google Translate

It Translated this:
206.340   Jordaen Willems de BROUWER
Familienaam • Index 206.340 • Vader 412.174 • Moeder 412.175 • Tevens 206.380, 412.258

Overleden voor 1485
Vermoedelijk al dood in 1463: ‘de kinderen van’ worden dan vermeld; 1468: het erf dat eerder van Joerden Sbrouwers was. In 1466 vermeld: erf van de kinderen Willem Brouwers. In 1470: vidimus van een akte uit 1429 met daarin “Joerden Jans de Brouwer als wettige man van Agnesen dochter van genoemde Dirck (van der Vloet)”

ORA Oirschot (Toirkens 126a fol 44 nos 208/209 dd resp Allerheiligen en St Hubertus 1493) Joerden Joerden Sbrouwerss heeft beloofd aan zijn broer Henrick die voortaan jaarlijks een pacht van 21 mud rogge te gaan betalen, maat van Oirschot, steeds vervallend op Maria Lichtmisdag, op onderpand van een huis, tuin etc,. gelegen onder Erdbruggen hier groot ca. een bunder, b.p. Gielis Stansen, Jan Wouters van de Loo, Peter Lanen, de erfgenamen van Heijlwich Heijmericks, de gemeenschappelijke straat. (Idem 209) Joerden Joerden Sbrouwers heeft beloofd aan Frank de Haest die voortaan een pacht van 1 mud rogge per jaar te gaan betalen, maat van Oirschot, steeds op Maria Lichtmisdag op onderpand van het hiervoor genoemde bezit onder Erdbruggen.

ORA Oirschot (Toirkens 126a fol 22 nos 125-6 dd 1-9-1495) Jonker Wernaert van Merode zoon van wijlen heer Ricalt van Merode verkoopt met brieven etc. aan Cornelis Smeeds ten behoeve van Henrick Joerden Brouwers een rente van 4 rijnsguldens per jaar, geslagen door de 4 Keurvorsten, met 5 achterstallige termijnen, welke rente Jan Jan Bruijstens en zijn wettige vrouw Aleijt eeder hadden beloofd aan heer Ricalt van Merode en diens vrouw Margriet van Arkenteel, steeds te betalen op St. Gielisdag op onderpand van een huis, tuin etc. gelegen onder Erdbruggen hier, b.p. Jan Brouwers, de gemeenschappelijke straat. Nog op onderpand van een beemd genoemd de Ter Meijenbeemd, groot ca. 3 en een halve bunder, b.p. Goijaert van Berckt, de erfgenamen van Goijaert van der Vloeten, de gemeenschappelijke straat. De verkoper namens de erfgenamen ook van heer Ricalt van Merode belooft alle lasten van zijn kant af te handelen. (Idem 126) Joerden de Brouwer belooft jonker Wernaert van Merode per a.s. Maria Lichtmisdag over een jaar, 40 rijnsguldens te betalen, waarbij de gouden rijnsgulden 25 stuivers is, etc. samen met een rente van 2 peters, elke peter tegen 18 stuivers.


ORA Oost- en Middelbeers (Transcriptie Jan Toirkens 1542-1553 fol 5r no 15 dd 14-4-1542) Jan zoon wijlen Jan de Cort door wijlen deze Jan de Cort verwekt bij diens vrouw Elisabeth wettige dochter van wijlen Joerden Sbrouwers, verder Mathijs zoon wijlen Dirck zoon wijlen Dirck Mesmakers door deze laatste wijlen Dirck verwekt bij diens vrouw Isabelle wettige dochter van Joerden Sbrouwers, voor hemzelf handelend en voor Dirck, Marie, Adriaan, Aleijt en Agnese zijn broers en zusters waarvoor hij optreedt, verder Henrick en Dirck broers en wettige kinderen van wijlen Willem van Berze door deze Willem verwekt bij zijn vrouw Marie wettige dochter van wijlen Simon Dircks, door deze Simon verwekt bij diens vrouw Agnesen wettige dochter van wijlen Joerden, verder Jan en Aert broers en wettige kinderen van wijlen Joerden zoon wijlen genoemde Joerden Sbrouwers, Wouter Jan Toerkens als man van Agnese wettige dochter van wijlen genoemde Joerden, voor henzelf handelend en voor Jan Philips van Herzele als man van Anna wettige dochter van wijlen genoemde Joerden, nog Willem Goijaert Aelbrechts als man van Aleijt wettige dochter van wijlen genoemde Joerden, verder Joerden zoon wijlen Henrick zoon wijlen Joerden Sbrouwers, voor hemzelf handelend en voor zijn zusters Elisabeth en Luijtgaerden, Jan Peter Stapels als wettige man van Marie, Mathijs Jan Hacken als wettige man van Agneees, beide wettige dochters van wijlen genoemde Henrick Brouwers, verder Joerden en Marcelis broers en wettige kinderen van wijlen Goijaert Marcelissen door deze Goijaert verwekt bij diens wettige vrouw Jacop wettige dochter van wijlen Henrick Sbrouwers, verder Henrick Jan Roggen als wettige man van Peter wettige dochter van wijlen genoemde Goijaert en Jacop, verder Jacop zoon wijlen Aert Zwanen als wettige man van Agnesen wettige dochter van wijlen Jacop Verheijden door deze Jacop verwekt bij diens vrouw Heijlwig, wettige dochter van genoemde Joerden Sbrouwers voor hemzelf handelend en voor Jan zoon wijlen genoemde Jacop en Heijlwig, verder Gijsbrecht zoon wijlen Pauwels Vlemmincks door deze Pauwels verwekt bij diens vrouw Heijlwig wettige dochter van Dirck zoon weijlen genoemde Jorden Sbrouwers, Henrick Dionijs Colen weduwnaar van wijlen Beelken wettige dochterr van wijlen genoemde Pauwels Vlemmincks, nog Jan wettige zoon van Henrik Dionijs Colen voor hemzelf handelend en voor Jan, Marten, Peter, Henrick Laureijs, Heijlwig, Aleijt en Elisabeth, zijnde alle kinderen van laatstgenoemde Henrick (Colen), nog Joest Willem Dionijs als wettige man van Cornelis wettige dochter van wijlen genoemde Pauwels Vlemmincks, Frank

To This:

206,340 Jordaen Willems de BROUWER
Surname • Index 206.340 • Father 412.174 • Mother 412.175 • Also 206.380, 412.258

Died before 1485
Presumably already dead in 1463: 'the children of' are then mentioned; 1468: the yard that was previously owned by Joerden Sbrouwers. In 1466 mentioned: yard of the children Willem Brouwers. In 1470: vidimus of a deed from 1429 containing "Joerden Jans de Brouwer as legal man of Agnesen's daughter Dirck (van der Vloet)"

ORA Oirschot (Toirkens 126a fol 44 nos 208/209 of All Saints and St Hubertus 1493) Joerden Joerden Sbrouwerss promised to his brother Henrick that from now on every year a rent of 21 mud rye to go, measure of Oirschot, always falling on Maria Lichtmisdag , on the basis of a house, garden etc ,. located under Erdbruggen here large approx. a bunder, b.p. Gielis Stansen, Jan Wouters van de Loo, Peter Lanen, the heys of Heijlwich Heijmericks, the common street. (Idem 209) Joerden Joerden Sbrouwers has promised to Frank de Haest that from now on a rent of 1 mud rye per year to pay, measure of Oirschot, always on Maria Lichtmisdag on the basis of the aforementioned property under Erdbruggen.

ORA Oirschot (Toirkens 126a fol 22 nos 125-6 dated 1-9-1495) Jonker Wernaert van Merode son of the late Mr. Ricalt van Merode sells letters to Cornelis Smeeds on behalf of Henrick Joerden Brouwers an interest of 4 tributes per year , beaten by the 4 Electors, with 5 overdue installments, which interest Jan Jan Bruijstens and his lawful wife Aleijt had promised to Mr. Ricalt van Merode and his wife Margriet van Arkenteel, to always pay on St. Gielisdag on the basis of a house, garden etc. located under Erdbruggen here, bp Jan Brouwers, the common street. Still on the collateral of a beemd called the Ter Meijenbeemd, large approx. 3 and a half bunder, b.p. Goijaert van Berckt, the heirs of Goijaert van der Vloeten, the common street. The seller on behalf of the heirs also of Mr. Ricalt van Merode promises to handle all the expenses on his part. (Ditto 126) Joerden de Brouwer promises youngster Wernaert van Merode per a.s. Maria Lichtmisdag over a year, pay 40 guilders, with the golden guilders 25 pennies, etc. together with an interest of 2 pars, each peter against 18 stivers.

ORA Oost- and Middelbeers (Transcription Jan Toirkens 1542-1553 fol 5r no 15 dd 14-4-1542) Jan son the late Jan de Cort by the late Jan de Cort fathered his wife Elisabeth legal daughter of the late Joerden Sbrouwers, further Mathijs son the late Dirck son the late Dirck Mesmakers by the latter late Dirck conceived with his wife Isabelle legal daughter of Joerden Sbrouwers, acting for him and for Dirck, Marie, Adriaan, Aleijt and Agnese his brothers and sisters for whom he acts, also Henrick and Dirck brothers and The legitimate children of the late Willem van Berze by this Willem fathered his wife Marie the legitimate daughter of the late Simon Dircks, fathered by his wife Agnesen's legitimate daughter of the late Joerden, furthermore Jan and Aert brothers and legal children of the late Joerden son mentioned Joerden Sbrouwers, Wouter Jan Toerkens as husband of Agnese legal daughter of the late Joerden, acting for them and for Jan Philips van Herzele as husband of Anna lawful daughter of the late Joerden, still Willem Goijaert Aelbrechts as husband of Aleijt's legitimate daughter of the late Joerden, further Joerden son the late Henrick son the late Joerden Sbrouwers, acting for himself and for his sisters Elisabeth and Luijtgaerden, Jan Peter Stapels as legal husband of Marie, Mathijs Jan Hacken as legal husband of Agneees, both legitimate daughters of the mentioned Henrick Brouwers, further Joerden and Marcelis brothers and legitimate children of the late Goijaert Marcelissen conceived by this Goijaert with his legal wife Jacop legal daughter of the late Henrick Sbrouwers, further Henrick Jan Roggen as legal husband of Peter legal daughter of the late Goijaert and Jacop, further Jacop son the late Aert Zwanen as legal husband of Agnesen legal daughter of the late Jacop Verheijden by this Jacop conceived by his wife Heijlwig, legal daughter of said Joerden Sbrouwers acting for himself and for Jan his late son named Jacop and Heijlwig, further Gijsbrecht son the late Pauwels Vlemmincks by these Pauwels conceived by his wife Heijlwig lawful daughter of Dirck son named Jorden Sbrouwers, Henrick Dionijs Colen widower of the late Beelken legal daughter of the late Pauwels Vlemmincks, still Jan legal son of Henrik Dionijs Colen acting for himself and for Jan, Marten, Peter, Henrick Laureijs, Heijlwig, Aleijt and Elisabeth, being all children of the latter Henrick (Colen), still Joest Willem Dionijs as legal husband of Cornelis legal daughter of the aforementioned Pauwels Vlemmincks, Frank

23 August 2018

365 Days a Year, 
365 Family History-Genealogy Rules 

13.

  Your DNA can give you a whole new way to look at yourself.

Finding family on Facebook and other Social Media.

What stories can you share with us?  Add a comment share your success or unfriendly story.
365 Days a Year, 
365 Family History-Genealogy Rules 

19.
Do you know who to pass on the genealogy to in your family.  Will it be one of your children grandchild, niece, nephew, or a great one of these.
365 Days a Year, 
365 Family History-Genealogy Rules 

12.
16 sets of Grandparents
{you thinking yet?}
365 Days a Year, 
365 Family History-Genealogy Rules 

11.
8 Sets of Grandparents
365 Days a Year, 
365 Family History-Genealogy Rules 

10. 
Four Sets of Grandparents
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